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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
4
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pubmed:dateCreated |
2005-3-7
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pubmed:abstractText |
A latex agglutination test to detect urinary antigens for visceral leishmaniasis (VL) was studied. In 204 patients with suspected VL, KAtex had a sensitivity of 95.2% with good agreement with microscopy smears but poor agreement with 4 different serology tests. It was also positive in 2 confirmed VL cases co-infected with HIV. In all K4tex-positive confirmed cases actively followed up after treatment, the test became negative 1 month after completion of treatment. While IC4tex had a specificity of 100% in healthy endemic and non-endemic controls, the direct agglutination test (DAT) was positive in 14% of the KAtex-negative healthy endemic controls. KAtex is a simple addition to the diagnostics of VL particularly at field level and as a complementary test for the diagnosis of VL in smear-negative cases with positive DAT results.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1020-3397
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
844-55
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15748081-Adolescent,
pubmed-meshheading:15748081-Adult,
pubmed-meshheading:15748081-Animals,
pubmed-meshheading:15748081-Antigens, Protozoan,
pubmed-meshheading:15748081-Case-Control Studies,
pubmed-meshheading:15748081-Child,
pubmed-meshheading:15748081-Child, Preschool,
pubmed-meshheading:15748081-Endemic Diseases,
pubmed-meshheading:15748081-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15748081-Female,
pubmed-meshheading:15748081-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:15748081-Humans,
pubmed-meshheading:15748081-Immunoblotting,
pubmed-meshheading:15748081-Infant,
pubmed-meshheading:15748081-Latex Fixation Tests,
pubmed-meshheading:15748081-Leishmania donovani,
pubmed-meshheading:15748081-Leishmaniasis, Visceral,
pubmed-meshheading:15748081-Male,
pubmed-meshheading:15748081-Middle Aged,
pubmed-meshheading:15748081-Parasitology,
pubmed-meshheading:15748081-Prognosis,
pubmed-meshheading:15748081-Sensitivity and Specificity,
pubmed-meshheading:15748081-Sudan
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pubmed:year |
2003
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pubmed:articleTitle |
Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan.
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pubmed:affiliation |
Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Validation Studies
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