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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2005-3-2
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pubmed:abstractText |
Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene in lung cancers are associated with increased sensitivity of these cancers to drugs that inhibit EGFR kinase activity. However, the role of such mutations in the pathogenesis of lung cancers is unclear.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1460-2105
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pubmed:author |
pubmed-author:FengZidingZ,
pubmed-author:FongKwun MKM,
pubmed-author:FujisawaTakehikoT,
pubmed-author:GazdarAdi FAF,
pubmed-author:HerzJoachimJ,
pubmed-author:JooFF,
pubmed-author:LeeHueiH,
pubmed-author:MinnaJohn DJD,
pubmed-author:NomuraMasaharuM,
pubmed-author:RothJack AJA,
pubmed-author:ShigematsuHisayukiH,
pubmed-author:ShimizuNobuyoshiN,
pubmed-author:SuzukiMakotoM,
pubmed-author:TakahashiTakaoT,
pubmed-author:ToyookaShinichiS,
pubmed-author:WistubaIgnacio III
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pubmed:issnType |
Electronic
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pubmed:day |
2
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
339-46
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15741570-Adenocarcinoma,
pubmed-meshheading:15741570-Asian Continental Ancestry Group,
pubmed-meshheading:15741570-Australia,
pubmed-meshheading:15741570-Carcinoma, Neuroendocrine,
pubmed-meshheading:15741570-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:15741570-DNA, Viral,
pubmed-meshheading:15741570-European Continental Ancestry Group,
pubmed-meshheading:15741570-Female,
pubmed-meshheading:15741570-Gene Duplication,
pubmed-meshheading:15741570-Genes, erbB-1,
pubmed-meshheading:15741570-Genes, ras,
pubmed-meshheading:15741570-Humans,
pubmed-meshheading:15741570-Japan,
pubmed-meshheading:15741570-Lung Neoplasms,
pubmed-meshheading:15741570-Male,
pubmed-meshheading:15741570-Mutagenesis, Insertional,
pubmed-meshheading:15741570-Mutation,
pubmed-meshheading:15741570-Mutation, Missense,
pubmed-meshheading:15741570-Neoplasm Staging,
pubmed-meshheading:15741570-Papillomaviridae,
pubmed-meshheading:15741570-Protein-Tyrosine Kinases,
pubmed-meshheading:15741570-Sequence Analysis, DNA,
pubmed-meshheading:15741570-Taiwan,
pubmed-meshheading:15741570-United States
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pubmed:year |
2005
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pubmed:articleTitle |
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
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pubmed:affiliation |
Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX 75390-8593, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study
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