Source:http://linkedlifedata.com/resource/pubmed/id/15741056
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2005-3-2
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pubmed:abstractText |
Glucose monitoring is an essential component of modern diabetes management. Three in vivo glucose sensors are now available for clinical use: a subcutaneously implanted amperometric enzyme electrode, a reverse iontophoresis system and a microdialysis-based device. Improvements in glucose-sensing technology continue to be sought, e.g. wired enzyme technology, viscometric affinity sensing and totally implanted glucose sensors. Non-invasive glucose sensing is the ultimate goal of glucose monitoring, but the most investigated approach, near-infrared (NIR) spectroscopy, is presently too imprecise for clinical application. Fluorescence-based glucose sensing offers several advantages and we are investigating strategies which include NIR-based fluorescence resonance energy transfer using concanavalin A/dextran; changes in the intrinsic fluorescence of hexokinase encapsulated in sol-gel; and non-invasive glucose monitoring of cells by measuring glucose-related changes in NADP(H).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0956-5663
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1897-902
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pubmed:dateRevised |
2009-7-14
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pubmed:meshHeading |
pubmed-meshheading:15741056-Biosensing Techniques,
pubmed-meshheading:15741056-Blood Glucose,
pubmed-meshheading:15741056-Blood Glucose Self-Monitoring,
pubmed-meshheading:15741056-Diabetes Mellitus,
pubmed-meshheading:15741056-Equipment Design,
pubmed-meshheading:15741056-Humans,
pubmed-meshheading:15741056-Microdialysis,
pubmed-meshheading:15741056-Miniaturization,
pubmed-meshheading:15741056-Monitoring, Ambulatory,
pubmed-meshheading:15741056-Spectrum Analysis
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pubmed:year |
2005
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pubmed:articleTitle |
In vivo glucose monitoring: the clinical reality and the promise.
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pubmed:affiliation |
Metabolic Unit, Guy's, King's and St Thomas's School of Medicine, Guy's Hospital, 5th Floor Thomas Guy House, London SE1 9RT, UK. john.pickup@kcl.ac.uk
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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