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rdf:type |
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lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0007124,
umls-concept:C0017262,
umls-concept:C0062505,
umls-concept:C0185117,
umls-concept:C0449560,
umls-concept:C0580822,
umls-concept:C0681841,
umls-concept:C1521991,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594,
umls-concept:C2911684
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pubmed:issue |
3
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pubmed:dateCreated |
2005-3-1
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pubmed:abstractText |
Ductal carcinoma in situ of the breast (DCIS) forms a heterogeneous group of lesions with varying invasive potential. This study tested whether heparanase-1 (HPR1), an endoglycosidase that specifically degrades the heparan sulfate (HS) proteoglycans in the breast extracellular matrix, was associated with the most aggressive DCIS subtypes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Heparin,
http://linkedlifedata.com/resource/pubmed/chemical/Polysaccharide-Lyases,
http://linkedlifedata.com/resource/pubmed/chemical/Proteoglycans,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/heparatinase I,
http://linkedlifedata.com/resource/pubmed/chemical/heparin proteoglycan
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1072-7515
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
200
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
328-35
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15737842-Antibodies, Monoclonal,
pubmed-meshheading:15737842-Antibodies, Neoplasm,
pubmed-meshheading:15737842-Breast Neoplasms,
pubmed-meshheading:15737842-Carcinoma, Ductal, Breast,
pubmed-meshheading:15737842-Carcinoma in Situ,
pubmed-meshheading:15737842-Extracellular Matrix,
pubmed-meshheading:15737842-Female,
pubmed-meshheading:15737842-Fluorescent Antibody Technique,
pubmed-meshheading:15737842-Follow-Up Studies,
pubmed-meshheading:15737842-Gene Expression,
pubmed-meshheading:15737842-Heparin,
pubmed-meshheading:15737842-Humans,
pubmed-meshheading:15737842-Immunohistochemistry,
pubmed-meshheading:15737842-Polysaccharide-Lyases,
pubmed-meshheading:15737842-Prognosis,
pubmed-meshheading:15737842-Proteoglycans,
pubmed-meshheading:15737842-Severity of Illness Index,
pubmed-meshheading:15737842-Tumor Markers, Biological
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pubmed:year |
2005
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pubmed:articleTitle |
Ductal carcinoma in situ of the breast and heparanase-1 expression: a molecular explanation for more aggressive subtypes.
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pubmed:affiliation |
Department of General Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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