rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2005-2-28
|
pubmed:abstractText |
Mutations of the TP53 gene have been associated with resistance to chemotherapy as well as poor prognosis in many different malignancies. This is the first prospective study of the prognostic value of somatic TP53 mutations in patients with newly diagnosed extremity osteosarcoma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0732-183X
|
pubmed:author |
pubmed-author:AndrulisIrene LIL,
pubmed-author:BeauchampChris PCP,
pubmed-author:BellRobert SRS,
pubmed-author:BullShelley BSB,
pubmed-author:ConradErnest UEU,
pubmed-author:DavisAileen MAM,
pubmed-author:EskandarianSashaS,
pubmed-author:GHIGIEE,
pubmed-author:GokgozNalanN,
pubmed-author:GrimerRobert JRJ,
pubmed-author:MalkinDavidD,
pubmed-author:ManghamD CDC,
pubmed-author:ParkesRobertR,
pubmed-author:RockMichael JMJ,
pubmed-author:WunderJay SJS
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1483-90
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15735124-Adolescent,
pubmed-meshheading:15735124-Adult,
pubmed-meshheading:15735124-Blotting, Southern,
pubmed-meshheading:15735124-Bone Neoplasms,
pubmed-meshheading:15735124-Genes, p53,
pubmed-meshheading:15735124-Humans,
pubmed-meshheading:15735124-Mutation,
pubmed-meshheading:15735124-Osteosarcoma,
pubmed-meshheading:15735124-Prospective Studies,
pubmed-meshheading:15735124-Treatment Outcome,
pubmed-meshheading:15735124-Tumor Markers, Biological
|
pubmed:year |
2005
|
pubmed:articleTitle |
TP53 mutations and outcome in osteosarcoma: a prospective, multicenter study.
|
pubmed:affiliation |
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5. wunder@mshri.on.ca
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|