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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2005-2-28
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pubmed:abstractText |
Akt is a serine/threonine kinase that leads to stimulation of cell cycle progression, cell proliferation, and inhibition of apoptosis. To investigate the role of Akt in melanoma pathogenesis, we examined the expression of phospho-Akt (p-Akt; Ser-473) in melanocytic lesions at different stages and analyzed the correlations between the p-Akt expression level and clinicopathologic factors and patient survival.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0732-183X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1473-82
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15735123-Disease Progression,
pubmed-meshheading:15735123-Disease-Free Survival,
pubmed-meshheading:15735123-Dysplastic Nevus Syndrome,
pubmed-meshheading:15735123-Female,
pubmed-meshheading:15735123-Humans,
pubmed-meshheading:15735123-Male,
pubmed-meshheading:15735123-Melanoma,
pubmed-meshheading:15735123-Middle Aged,
pubmed-meshheading:15735123-Neoplasm Invasiveness,
pubmed-meshheading:15735123-Neoplasm Metastasis,
pubmed-meshheading:15735123-Nevus,
pubmed-meshheading:15735123-Prognosis,
pubmed-meshheading:15735123-Protein-Serine-Threonine Kinases,
pubmed-meshheading:15735123-Proto-Oncogene Proteins,
pubmed-meshheading:15735123-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:15735123-Skin Neoplasms,
pubmed-meshheading:15735123-Survival Rate,
pubmed-meshheading:15735123-Tumor Markers, Biological
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pubmed:year |
2005
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pubmed:articleTitle |
Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases.
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pubmed:affiliation |
Department of Medicine, Division of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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