Linked Life Data

15734653

Source:http://linkedlifedata.com/resource/pubmed/id/15734653

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2005-2-28
pubmed:abstractText
Human filarial nematodes cause river blindness and lymphatic filariasis, both of which are diseases that produce considerable morbidity. Control of these diseases relies on drug treatments that are ineffective against macrofilariae and are threatened by the development of resistance. New validated drug targets are required to allow development of new classes of antifilarial drugs. To identify and validate potential new drug targets, we propose a collaborative research strategy utilizing bioinformatic filters and assessment of gene function by RNA interference in Caenorhabditis elegans and Brugia malayi.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1471-4922
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-100
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
RNAi-based discovery and validation of new drug targets in filarial nematodes.
pubmed:affiliation
School of Biochemistry and Molecular Biology, Faculty of Science, Australian National University, Canberra 0200, Australia. Carolyn.Behm@anu.edu.au
pubmed:publicationType
Journal Article, Review