Linked Life Data

15733341

Source:http://linkedlifedata.com/resource/pubmed/id/15733341

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-2-28
pubmed:abstractText
Acetylcholine, acting through nicotinic acetylcholine receptors, mediates the response properties of many ganglion cells in the rabbit retina, including those that are directionally selective (DS; Ariel & Daw, 1982a, b). For example, Grzywacz et al. (1998) showed that cholinergic input is necessary for DS responses to drifting gratings, a form of textured stimulus. However, the identities and locations of the neuronal acetylcholine receptor (nAChR) subtypes that mediate this input are not clear (Keyser et al., 2000). We investigated the role of methyllycaconitine-sensitive, alpha7-like nAChRs in mediating DS responses to textured stimuli and apparent motion. We recorded extracellularly from On-Off DS ganglion cells in rabbit retina using everted eyecup preparations. Our data provide evidence that MLA-sensitive nAChRs are involved in mediating directionally selective responses to apparent motion and to a variety of complex, textured stimuli such as drifting square-wave gratings, transparent motion, and second-order motion.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0952-5238
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
861-72
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
MLA-sensitive cholinergic receptors involved in the detection of complex moving stimuli in retina.
pubmed:affiliation
Vision Science Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-4390, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.