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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-2-28
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pubmed:abstractText |
Estramustine phosphate sodium (EMP) frequently causes side-effects such as gastrointestinal discomfort, nausea, and edema in extremities. We analyzed single nucleotide polymorphisms (SNP) in the 17beta-hydroxysteroid dehydrogenase (HSD17B) genes, which are involved in the metabolism of EMP, to predict the risk of EMP side-effects in prostate cancer patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0919-8172
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15733111-17-Hydroxysteroid Dehydrogenases,
pubmed-meshheading:15733111-Aged,
pubmed-meshheading:15733111-Aged, 80 and over,
pubmed-meshheading:15733111-Antineoplastic Agents, Hormonal,
pubmed-meshheading:15733111-Appetite,
pubmed-meshheading:15733111-Edema,
pubmed-meshheading:15733111-Estramustine,
pubmed-meshheading:15733111-Gene Frequency,
pubmed-meshheading:15733111-Genotype,
pubmed-meshheading:15733111-Haplotypes,
pubmed-meshheading:15733111-Humans,
pubmed-meshheading:15733111-Male,
pubmed-meshheading:15733111-Middle Aged,
pubmed-meshheading:15733111-Polymorphism, Single Nucleotide,
pubmed-meshheading:15733111-Prostatic Neoplasms,
pubmed-meshheading:15733111-Risk Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Single-nucleotide polymorphisms in the 17beta-hydroxysteroid dehydrogenase genes might predict the risk of side-effects of estramustine phosphate sodium in prostate cancer patients.
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pubmed:affiliation |
Department of Urology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan. SUZUKIM-URO@h.u-tokyo.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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