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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-3-18
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pubmed:abstractText |
The acute-phase proteins, serum amyloid As (SAA), are precursors of amyloid A, involved in the pathogenesis of AA amyloidosis. This work started with the characterisation of systemic AA amyloidosis concurrent with SAA overexpression in the subcutaneous white adipose tissue (sWAT) of an obese patient with a leptin receptor deficiency. In the present study a series of histopathological, cellular and gene expression studies was performed to assess the importance of SAA in common obesity and its possible production by mature adipocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0012-186X
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pubmed:author |
pubmed-author:BarshG SGS,
pubmed-author:BasdevantAA,
pubmed-author:BrunevalPP,
pubmed-author:CancelloRR,
pubmed-author:CintiSS,
pubmed-author:ClémentKK,
pubmed-author:CourtineMM,
pubmed-author:CoussieuCC,
pubmed-author:De MatteisRR,
pubmed-author:GauthierEE,
pubmed-author:LanginDD,
pubmed-author:PoitouCC,
pubmed-author:SarinPP,
pubmed-author:StichVV,
pubmed-author:ViguerieNN,
pubmed-author:ZuckerJ DJD
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
519-28
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15729583-Adipocytes,
pubmed-meshheading:15729583-Adult,
pubmed-meshheading:15729583-Diet, Reducing,
pubmed-meshheading:15729583-Energy Intake,
pubmed-meshheading:15729583-Female,
pubmed-meshheading:15729583-Gene Expression Profiling,
pubmed-meshheading:15729583-Humans,
pubmed-meshheading:15729583-Nutritional Physiological Phenomena,
pubmed-meshheading:15729583-Nutritional Status,
pubmed-meshheading:15729583-Obesity,
pubmed-meshheading:15729583-Premenopause,
pubmed-meshheading:15729583-Receptors, Cell Surface,
pubmed-meshheading:15729583-Receptors, Leptin,
pubmed-meshheading:15729583-Reference Values,
pubmed-meshheading:15729583-Serum Amyloid A Protein,
pubmed-meshheading:15729583-Skin
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pubmed:year |
2005
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pubmed:articleTitle |
Serum amyloid A: production by human white adipocyte and regulation by obesity and nutrition.
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pubmed:affiliation |
Department of Nutrition and Biochemistry, French Institute of Health and Medical Research Avenir, EA 3502, Paris VI University, Hôtel-Dieu Hospital, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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