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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2005-2-24
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pubmed:abstractText |
Chronic immunosuppressive (IS) therapy impairs normal T-cell immune surveillance and may predispose to opportunistic infections and malignancies that represent life-threatening complication of solid-organ transplantation (SOTx). Our study was designed to ascertain the impact of chronic in vivo administration of IS on the ability of monocyte-derived dendritic cells (MoDC) to differentiate, mature, and function ex vivo. The potential of these cells to be implemented for DC-based adoptive immunotherapy was also considered.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD11c,
http://linkedlifedata.com/resource/pubmed/chemical/CD83 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQ Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0041-1337
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pubmed:author |
pubmed-author:Abu-ElmagdKareemK,
pubmed-author:BerghausJan MuellerJM,
pubmed-author:FungJohn JJJ,
pubmed-author:LuLinaL,
pubmed-author:MacedoCamilaC,
pubmed-author:MetesDianaD,
pubmed-author:PopescuIuliaI,
pubmed-author:ReyesJorgeJ,
pubmed-author:ShapiroRonR,
pubmed-author:StorkusWalter JWJ,
pubmed-author:ThomsonAngus WAW,
pubmed-author:WangLian FuLF,
pubmed-author:ZeeviAdrianaA
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
451-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15729172-Active Transport, Cell Nucleus,
pubmed-meshheading:15729172-Adult,
pubmed-meshheading:15729172-Antigens, CD,
pubmed-meshheading:15729172-Antigens, CD11c,
pubmed-meshheading:15729172-Cell Differentiation,
pubmed-meshheading:15729172-Cell Line,
pubmed-meshheading:15729172-Cell Polarity,
pubmed-meshheading:15729172-Cytokines,
pubmed-meshheading:15729172-Dendritic Cells,
pubmed-meshheading:15729172-HLA-DQ Antigens,
pubmed-meshheading:15729172-Humans,
pubmed-meshheading:15729172-Immunoglobulins,
pubmed-meshheading:15729172-Immunosuppressive Agents,
pubmed-meshheading:15729172-Immunotherapy, Adoptive,
pubmed-meshheading:15729172-Lymphocyte Activation,
pubmed-meshheading:15729172-Membrane Glycoproteins,
pubmed-meshheading:15729172-Monocytes,
pubmed-meshheading:15729172-NF-kappa B,
pubmed-meshheading:15729172-Organ Transplantation
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pubmed:year |
2005
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pubmed:articleTitle |
Augmentation of type-1 polarizing ability of monocyte-derived dendritic cells from chronically immunosuppressed organ-transplant recipients.
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pubmed:affiliation |
The Thomas E. Starzl Transplantation Institute, University of Pittsburgh, E1551 Biomedical Science Tower, 200 Lothrop Street, Pittsburgh, PA 15261, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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