Linked Life Data

15721800

Source:http://linkedlifedata.com/resource/pubmed/id/15721800

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-2-21
pubmed:abstractText
Studies in rodents have demonstrated that glucocorticoids enhance memory consolidation but impair delayed memory retrieval. Similar findings have been reported in humans. Emotional items are better remembered than neutral items. However, it is unknown if emotional valence influences the effects of cortisol on retrieval. In this double-blind crossover study, 16 healthy women learned a wordlist containing 15 neutral and 15 negative words. Delayed recall was tested 5h later. Cortisol administered before recall testing significantly reduced retrieval (p<.01). Exploratory follow-up analysis revealed that cortisol significantly impaired retrieval of negative words (p<.01), while having no significant effect on neutral words (p=.47). The current findings could suggest that emotional material is especially sensitive to the memory modulating effects of stress hormones.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1074-7427
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
158-62
pubmed:dateRevised
2007-10-17
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Effects of oral cortisol treatment in healthy young women on memory retrieval of negative and neutral words.
pubmed:affiliation
Institute of Experimental Psychology, University of Duesseldorf, Germany.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't