Linked Life Data

15719195

Source:http://linkedlifedata.com/resource/pubmed/id/15719195

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2005-5-11
pubmed:abstractText
Toxaphene, an organochlorine pesticide, is the major contaminant of Arctic charr (Salvelinus alpinus) in the Canadian Arctic. The objective of this study was to investigate the combined effects of toxaphene exposure and infection by the larval stage of the cestode Diphyllobothrium dendriticum on fish growth, nutritional composition, and hematology. Hatchery-reared Arctic charr were subjected to one of four treatments: (1) oral administration of corn oil (control); (2) single oral dose of 10 microg/g wet wt toxaphene dissolved in corn oil; (3) exposure to 15 larval D. dendriticum; and (4) exposure to toxaphene and D. dendriticum in combination. The experiment was run for 104 days. Mean final toxaphene concentrations in charr muscle were 0.121, 0.336, 0.131 and 0.458 microg/g wet wt in each treatment group, respectively. Exposure to toxaphene and D. dendriticum decreased fish growth and condition as well muscle lipid and protein content. However, toxaphene did not increase the susceptibility of Arctic charr to parasite infection. Overall, 25 of 40 fish (62.5%) exposed to larval D. dendriticum became infected. Parasitized charr had decreased hematocrits and increased lymphocyte:erythrocyte ratios. Although total blood cell counts were decreased in all treatments compared with controls, differential leucocyte counts were unaffected. Our results suggest that toxaphene does not moderate Arctic charr resistance to D. dendriticum and there is no contaminant-parasite interaction at environmental levels.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0090-4341
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
397-404
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Growth, nutritional composition, and hematology of Arctic charr (Salvelinus alpinus) exposed to toxaphene and tapeworm (Diphyllobothrium dendriticum) larvae.
pubmed:affiliation
Department of Natural Resource Sciences, MacDonald Campus, McGill University, Ste. Anne de Bellevue, Quebec, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't