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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2005-2-17
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pubmed:abstractText |
Epstein-Barr virus (EBV) DNA loads in peripheral blood mononuclear cells (PBMCs), plasma, and saliva, as well as infectivity of the virus in saliva, were evaluated in 20 patients for 6 months after the onset of infectious mononucleosis (IM). All patients displayed sustained high EBV DNA loads in the saliva, associated with a persistent infectivity of saliva at day 180. EBV DNA load in PBMCs decreased significantly from day 0 to day 180 (in spite of a viral rebound between day 30 and day 90 in 90% of the patients), and EBV DNA rapidly disappeared from plasma. These data show that patients with IM remain highly infectious during convalescence.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:BaccardMoniqueM,
pubmed-author:BrionJean-PaulJP,
pubmed-author:Fafi-KremerSamiraS,
pubmed-author:GenoulazOdileO,
pubmed-author:GermiRaphaeleR,
pubmed-author:JolivetMichelM,
pubmed-author:MorandPatriceP,
pubmed-author:NicodSandrineS,
pubmed-author:PavesePatriciaP,
pubmed-author:RuigrokRob W HRW,
pubmed-author:SeigneurinJean-MarieJM,
pubmed-author:StahlJean-PaulJP
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pubmed:issnType |
Print
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pubmed:day |
15
|
|
pubmed:volume |
191
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
985-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15717276-Adolescent,
pubmed-meshheading:15717276-Adult,
pubmed-meshheading:15717276-DNA, Viral,
pubmed-meshheading:15717276-Female,
pubmed-meshheading:15717276-Herpesvirus 4, Human,
pubmed-meshheading:15717276-Humans,
pubmed-meshheading:15717276-Infectious Mononucleosis,
pubmed-meshheading:15717276-Leukocytes, Mononuclear,
pubmed-meshheading:15717276-Male,
pubmed-meshheading:15717276-Saliva,
pubmed-meshheading:15717276-Time Factors,
pubmed-meshheading:15717276-Viral Load,
pubmed-meshheading:15717276-Virus Shedding
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pubmed:year |
2005
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pubmed:articleTitle |
Long-term shedding of infectious epstein-barr virus after infectious mononucleosis.
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pubmed:affiliation |
Laboratoire de Virologie Moléculaire et Structurale, EA 2939, Universite Joseph Fourier, Centre Hospitalier Universitaire, Grenoble, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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