Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-2-16
pubmed:abstractText
Distal vein cuff interposition is often added to prosthetic infragenicular arterial reconstruction in an attempt to improve hemodynamics and patency rates. The purpose of this study was to compare the outcome of a precuffed expanded polytetrafluroethylene (ePTFE) graft with a vein-cuffed ePTFE graft for infragenicular bypass. We reviewed the clinical outcome of 77 patients with critical limb ischemia without available autologous vein conduits who underwent arterial reconstruction of 80 limbs to below-knee popliteal or tibioperoneal vessels using either ePTFE precuffed graft (precuffed group, 38 patients 40 limbs) or ePTFE vein-cuffed graft (vein-cuffed group, 39 patient, 40 limbs). Precuffed group patients were enrolled in a prospective cohort study. Vein-cuffed group patients consisted of consecutive case-matched patients operated on during the same study period. End points were primary graft patency and limb salvage rates. There were 42 males and 35 females with a mean age of 73.4 years (range, 44-92 years). Both groups were matched to demographics, risk factors for atherosclerosis, previous ipsilateral reconstruction, and location of the distal anastomosis. Proximal anastomosis was to the common (n = 68) or superficial (n = 12) femoral arteries. Distal anastomosis was to the below-knee popliteal (n = 28), anterior tibial (n = 12), posterior tibial (n = 15) and peroneal (n = 25) arteries. Operative mortality was 1.3%. Graft patency at dismissal was 90% and 95% in the precuffed and vein-cuffed groups, respectively. The mean follow-up was 25.7 months (range, 2.4-61 months). Primary patency rates at 1 and 3 years were 70% and 57% in the precuffed group, and 78% and 54% in the vein-cuffed group (p = 0.32). Limb salvage rates at 1 and 3 years were 97% and 70% in the precuffed group, and 95% and 81% in the vein-cuffed group (p = 0.49). Overall patient survival at 1 and 3 years was 81 % and 57%, respectively. In this case-control study, results of precuffed ePTFE graft were similar to those obtained with vein-cuffed ePTFE grafts. The precuffed ePTFE graft is an adequate alternative conduit for infragenicular arterial reconstruction in patients with critical limb ischemia and no available autologous veins.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0890-5096
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-55
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:15714367-Adult, pubmed-meshheading:15714367-Aged, pubmed-meshheading:15714367-Aged, 80 and over, pubmed-meshheading:15714367-Anastomosis, Surgical, pubmed-meshheading:15714367-Blood Vessel Prosthesis, pubmed-meshheading:15714367-Blood Vessel Prosthesis Implantation, pubmed-meshheading:15714367-Case-Control Studies, pubmed-meshheading:15714367-Cohort Studies, pubmed-meshheading:15714367-Female, pubmed-meshheading:15714367-Femoral Artery, pubmed-meshheading:15714367-Follow-Up Studies, pubmed-meshheading:15714367-Humans, pubmed-meshheading:15714367-Ischemia, pubmed-meshheading:15714367-Leg, pubmed-meshheading:15714367-Male, pubmed-meshheading:15714367-Middle Aged, pubmed-meshheading:15714367-Polytetrafluoroethylene, pubmed-meshheading:15714367-Popliteal Artery, pubmed-meshheading:15714367-Prospective Studies, pubmed-meshheading:15714367-Prosthesis Design, pubmed-meshheading:15714367-Risk Factors, pubmed-meshheading:15714367-Survival Rate, pubmed-meshheading:15714367-Tibial Arteries, pubmed-meshheading:15714367-Treatment Outcome, pubmed-meshheading:15714367-Vascular Patency
pubmed:year
2005
pubmed:articleTitle
Comparison of precuffed and vein-cuffed expanded polytetrafluoroethylene grafts for infragenicular arterial reconstructions: a case-matched study.
pubmed:affiliation
Division of Vascular Surgery, Mayo Clinic, Rochester, MN, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study