Source:http://linkedlifedata.com/resource/pubmed/id/15714188
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2005-2-16
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| pubmed:abstractText |
This study evaluates the prevalence of threshold and subthreshold use of substances among patients with psychiatric disorders and 2 comparison groups. Participants were outpatients and inpatients with mood and anxiety disorders, subjects with opiate dependence, and a comparison group of individuals not undergoing treatment for psychiatric disorders. Assessments included the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition , Axis I Disorders, an interview exploring the spectrum of substance use (Structured Clinical Interview for the Spectrum of Substance Use), and a self-report instrument exploring the spectrum of 5 psychiatric disorders (General 5-Spectrum Measure). The overall frequency of substance use disorder (SUD) and that of subthreshold use were 46% and 8% in patients with bipolar disorder, 4% and 26% in those with panic disorder, 8% and 26% in those with obsessive-compulsive disorder, and 6% and 10% in the control group, respectively ( Idouble dagger 2 = 51.6, P < .001). Inspection of standardized residuals indicated that alcohol use disorder and SUD were significantly ( P < .05) more frequent in subjects with bipolar disorder than among those with obsessive-compulsive disorder or panic disorder. The latter showed a significantly higher subthreshold use of substances than control subjects. The pattern of motivations for use varied according to the psychiatric disorder. Our results suggest that the well-established relationship between SUDs and psychiatric disorders might be the end point of a process that starts from increased proneness to substance use, which first leads to self-medication and then may eventually develop into substance abuse or dependence, among subjects with psychiatric symptoms.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:issn |
0010-440X
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| pubmed:author |
pubmed-author:BizzarriJacopo VittorianoJV,
pubmed-author:CassanoGiovanni BattistaGB,
pubmed-author:Dell'OssoLillianaL,
pubmed-author:DoriaMaria RosaMR,
pubmed-author:GonnelliChiaraC,
pubmed-author:RaimondiFedericaF,
pubmed-author:RavaniLauraL,
pubmed-author:RucciPaolaP,
pubmed-author:SbranaAlfredoA,
pubmed-author:SpagnolliSabrinaS
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| pubmed:issnType |
Print
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| pubmed:volume |
46
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
6-13
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| pubmed:meshHeading |
pubmed-meshheading:15714188-Adolescent,
pubmed-meshheading:15714188-Adult,
pubmed-meshheading:15714188-Ambulatory Care,
pubmed-meshheading:15714188-Anxiety Disorders,
pubmed-meshheading:15714188-Bipolar Disorder,
pubmed-meshheading:15714188-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:15714188-Female,
pubmed-meshheading:15714188-Hospitalization,
pubmed-meshheading:15714188-Humans,
pubmed-meshheading:15714188-Interview, Psychological,
pubmed-meshheading:15714188-Male,
pubmed-meshheading:15714188-Middle Aged,
pubmed-meshheading:15714188-Mood Disorders,
pubmed-meshheading:15714188-Obsessive-Compulsive Disorder,
pubmed-meshheading:15714188-Panic Disorder,
pubmed-meshheading:15714188-Prevalence,
pubmed-meshheading:15714188-Substance-Related Disorders
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| pubmed:articleTitle |
The spectrum of substance use in mood and anxiety disorders.
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| pubmed:affiliation |
Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, 56127 Pisa, Italy. alfredosbrana@virgilio.it
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| pubmed:publicationType |
Journal Article
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