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15713389
Source:
http://linkedlifedata.com/resource/pubmed/id/15713389
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0003374
,
umls-concept:C0035647
,
umls-concept:C0205314
,
umls-concept:C0205460
,
umls-concept:C0220781
,
umls-concept:C0220825
,
umls-concept:C0282215
,
umls-concept:C0679622
,
umls-concept:C1707689
,
umls-concept:C1883254
pubmed:issue
5
pubmed:dateCreated
2005-2-16
pubmed:abstractText
A series of bicyclic N-substituted and unsubstituted beta-lactams were synthesized and evaluated as targeted potential antimalarials. The compounds MNR4 and MNR5 were found to have highest potency against Plasmodium falciparum in vitro.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials
,
http://linkedlifedata.com/resource/pubmed/chemical/Bicyclo Compounds
,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Lactams
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0960-894X
pubmed:author
pubmed-author:KaushikM PMP
,
pubmed-author:NivsarkarManishaM
,
pubmed-author:PrasannaSS
,
pubmed-author:SharmaMamtaM
,
pubmed-author:ThavaselvamDD
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1371-3
pubmed:meshHeading
pubmed-meshheading:15713389-Animals
,
pubmed-meshheading:15713389-Antimalarials
,
pubmed-meshheading:15713389-Bicyclo Compounds
,
pubmed-meshheading:15713389-Drug Design
,
pubmed-meshheading:15713389-Drug Evaluation, Preclinical
,
pubmed-meshheading:15713389-Humans
,
pubmed-meshheading:15713389-Magnetic Resonance Spectroscopy
,
pubmed-meshheading:15713389-Molecular Structure
,
pubmed-meshheading:15713389-Parasitic Sensitivity Tests
,
pubmed-meshheading:15713389-Plasmodium falciparum
,
pubmed-meshheading:15713389-Structure-Activity Relationship
,
pubmed-meshheading:15713389-beta-Lactams
pubmed:year
2005
pubmed:articleTitle
Design, synthesis and biological evaluation of novel bicyclic beta-lactams as potential antimalarials.
pubmed:affiliation
Process Technology Development Division, Defence R&D Establishment, Jhansi Road, Gwalior 474002, MP, India.
pubmed:publicationType
Journal Article