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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2005-3-8
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pubmed:abstractText |
Over-expression of the oncogene c-Myc has been implicated in the development and progression of human prostate carcinoma. However, previous assessments of c-Myc expression have not revealed its potential for predicting prostate carcinoma progression. Caveolin-1 is associated with prostate carcinoma progression and is a downstream target gene of c-Myc. The observation that caveolin-1 can suppress c-Myc-induced apoptosis suggested the potential for cooperation between c-Myc and caveolin-1 in malignant progression. In this study, the authors evaluated the prognostic potential of combined c-Myc and caveolin-1 expression in human prostate carcinoma progression.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1186-94
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15712208-Adenocarcinoma,
pubmed-meshheading:15712208-Age Distribution,
pubmed-meshheading:15712208-Aged,
pubmed-meshheading:15712208-Biopsy, Needle,
pubmed-meshheading:15712208-Caveolin 1,
pubmed-meshheading:15712208-Caveolins,
pubmed-meshheading:15712208-Cohort Studies,
pubmed-meshheading:15712208-Confidence Intervals,
pubmed-meshheading:15712208-Disease Progression,
pubmed-meshheading:15712208-Humans,
pubmed-meshheading:15712208-Immunohistochemistry,
pubmed-meshheading:15712208-Male,
pubmed-meshheading:15712208-Middle Aged,
pubmed-meshheading:15712208-Predictive Value of Tests,
pubmed-meshheading:15712208-Probability,
pubmed-meshheading:15712208-Prognosis,
pubmed-meshheading:15712208-Proportional Hazards Models,
pubmed-meshheading:15712208-Prostatectomy,
pubmed-meshheading:15712208-Prostatic Neoplasms,
pubmed-meshheading:15712208-Proto-Oncogene Proteins c-myc,
pubmed-meshheading:15712208-Risk Assessment,
pubmed-meshheading:15712208-Sensitivity and Specificity,
pubmed-meshheading:15712208-Survival Analysis,
pubmed-meshheading:15712208-Tissue Culture Techniques,
pubmed-meshheading:15712208-Treatment Outcome,
pubmed-meshheading:15712208-Tumor Markers, Biological
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pubmed:year |
2005
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pubmed:articleTitle |
Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression.
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pubmed:affiliation |
Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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