|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2005-2-15
|
|
pubmed:abstractText |
In 20 patients with myeloid malignancies and isolated trisomy 11 an internal tandem duplication of the MLL and FLT3 genes was observed in 41% and 31% of the cases, respectively; 80% of the FLT3+ cases showed MLL self-fusion. Concomitant presence of MLL and FLT3 anomalies could be relevant in determining the poor outcome of patients with acute myeloid leukemia with trisomy 11.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1592-8721
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
90
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
262-4
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:15710585-Adult,
pubmed-meshheading:15710585-Aged,
pubmed-meshheading:15710585-Aged, 80 and over,
pubmed-meshheading:15710585-Chromosomes, Human, Pair 11,
pubmed-meshheading:15710585-Gene Duplication,
pubmed-meshheading:15710585-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15710585-Humans,
pubmed-meshheading:15710585-Karyotyping,
pubmed-meshheading:15710585-Leukemia, Myeloid,
pubmed-meshheading:15710585-Middle Aged,
pubmed-meshheading:15710585-Myeloid-Lymphoid Leukemia Protein,
pubmed-meshheading:15710585-Time Factors,
pubmed-meshheading:15710585-Trisomy,
pubmed-meshheading:15710585-fms-Like Tyrosine Kinase 3
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Trisomy 11 in myeloid malignancies is associated with internal tandem duplication of both MLL and FLT3 genes.
|
|
pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
|
