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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-2-15
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pubmed:abstractText |
High levels of erythrocyte destruction in sickle cell anemia (SCA) result in chronic hyperbilirubinemia, with cholelithiasis occurring in a subset of patients. We investigated whether susceptibility to cholelithiasis in SCA was associated with the promoter polymorphism of the 5?-diphosphate-glucuronosyltransferase 1A1 (UGT1A1) gene encoding a key enzyme in bilirubin catabolism.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1592-8721
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
188-99
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:15710570-Adolescent,
pubmed-meshheading:15710570-Adult,
pubmed-meshheading:15710570-Age of Onset,
pubmed-meshheading:15710570-Anemia, Sickle Cell,
pubmed-meshheading:15710570-Child,
pubmed-meshheading:15710570-Child, Preschool,
pubmed-meshheading:15710570-Cholelithiasis,
pubmed-meshheading:15710570-Female,
pubmed-meshheading:15710570-Genotype,
pubmed-meshheading:15710570-Glucuronosyltransferase,
pubmed-meshheading:15710570-Hemoglobins,
pubmed-meshheading:15710570-Humans,
pubmed-meshheading:15710570-Male,
pubmed-meshheading:15710570-Middle Aged,
pubmed-meshheading:15710570-Polymorphism, Genetic,
pubmed-meshheading:15710570-Promoter Regions, Genetic,
pubmed-meshheading:15710570-Risk Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Association of UGT1A1 polymorphism with prevalence and age at onset of cholelithiasis in sickle cell anemia.
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pubmed:affiliation |
UMR S-458 INSERM/Université des Antilles et de la Guyane, France.
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pubmed:publicationType |
Journal Article
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