|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2 Pt 1
|
|
pubmed:dateCreated |
2005-2-9
|
|
pubmed:abstractText |
Gamma-catenin is a cell adhesion protein, and its functional loss is associated with tumor invasion and metastasis. We hypothesize that (1) promoter CpG methylation regulates the expression and function of the gamma-catenin gene in renal cell carcinoma (RCC) and (2) methylation of the gamma-catenin gene is associated with poor prognosis of RCC. To test these hypotheses, we analyzed the CpG methylation status of the gamma-catenin gene and its correlation with clinical outcome in RCC.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
pubmed-author:BreaultJulia EJE,
pubmed-author:CarrollPeter RPR,
pubmed-author:DahiyaRajvirR,
pubmed-author:DeguchiMasaoM,
pubmed-author:EnokidaHidekiH,
pubmed-author:IgawaMikioM,
pubmed-author:KaneChristopher JCJ,
pubmed-author:NakagawaMasayukiM,
pubmed-author:Ribeiro-FilhoLeopoldo ALA,
pubmed-author:ShiinaHiroakiH,
pubmed-author:TerashimaMasaharuM,
pubmed-author:UrakamiShinjiS
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
557-64
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:15701841-Adult,
pubmed-meshheading:15701841-Aged,
pubmed-meshheading:15701841-Aged, 80 and over,
pubmed-meshheading:15701841-Azacitidine,
pubmed-meshheading:15701841-Carcinoma, Renal Cell,
pubmed-meshheading:15701841-CpG Islands,
pubmed-meshheading:15701841-Cytoskeletal Proteins,
pubmed-meshheading:15701841-DNA, Neoplasm,
pubmed-meshheading:15701841-DNA Methylation,
pubmed-meshheading:15701841-Desmoplakins,
pubmed-meshheading:15701841-Disease Progression,
pubmed-meshheading:15701841-Enzyme Inhibitors,
pubmed-meshheading:15701841-Female,
pubmed-meshheading:15701841-Humans,
pubmed-meshheading:15701841-Kidney,
pubmed-meshheading:15701841-Kidney Neoplasms,
pubmed-meshheading:15701841-Male,
pubmed-meshheading:15701841-Middle Aged,
pubmed-meshheading:15701841-Mutation,
pubmed-meshheading:15701841-Prognosis,
pubmed-meshheading:15701841-Promoter Regions, Genetic,
pubmed-meshheading:15701841-Survival Rate,
pubmed-meshheading:15701841-gamma Catenin
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma.
|
|
pubmed:affiliation |
Department of Urology, Veterans Affairs Medical Center and University of California at San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|
