Linked Life Data

15701555

Source:http://linkedlifedata.com/resource/pubmed/id/15701555

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-2-9
pubmed:abstractText
This article emphasizes that for many controversial reasons, severe malaria in travelers differs from that seen in endemic areas. There is no controversy, however, that malaria in individuals living in endemic areas should retain research priority. Some of the questions raised might never be amenable to randomized controlled trials, either because of ethical or logistical restraints. A possibly indulgent wish list of outcome (mortality) studies using currently known treatment modalities, however, includes the loading dose of quinine, vigorous fluid replacement, ET, the artemisinins, mannitol, and N-acetylcysteine in the treatment of severe malaria. There may clearly be many more. The treatment of severe malaria remains a challenge to those with an interest in managing life-threatening disease with complex and fascinating pathophysiology. As challenging as the studies listed previously may seem, however, priority must inevitably be given to research on how one can prevent and treat mild disease in the first place.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0891-5520
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-40
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Management of severe malaria: interventions and controversies.
pubmed:affiliation
Department of Infection and Tropical Medicine, Lister Unit, Northwick Park Hospital, Harrow HA1 3UJ, UK. g.pasvol@imperial.ac.uk
pubmed:publicationType
Journal Article, Review