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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1979-9-27
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Abortion, Spontaneous,
http://linkedlifedata.com/resource/pubmed/keyword/CHROMOSOME ABNORMALITIES,
http://linkedlifedata.com/resource/pubmed/keyword/Comparative Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors,
http://linkedlifedata.com/resource/pubmed/keyword/Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/Fetal Death,
http://linkedlifedata.com/resource/pubmed/keyword/Genetics,
http://linkedlifedata.com/resource/pubmed/keyword/Infant Mortality,
http://linkedlifedata.com/resource/pubmed/keyword/Mortality,
http://linkedlifedata.com/resource/pubmed/keyword/Neonatal Diseases And Abnormalities,
http://linkedlifedata.com/resource/pubmed/keyword/Population,
http://linkedlifedata.com/resource/pubmed/keyword/Population Dynamics,
http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy Complications,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Studies
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0300-1652
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-92
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pubmed:dateRevised |
2011-9-30
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pubmed:otherAbstract |
PIP: In a comparative study to ascertain the effect of Down's Syndrome on pregnancy wastage in mothers, 62 mothers of Down's Syndrome babies were matched with 62 control mothers on the basis of maternal age and live-birth order. The hospital case notes for the 124 women were consulted. There was no significant difference in the fertility of the 2 groups. 3.57% of total pregnancies ended in stillbirth for the case group as opposed to .33% for the control group. 6.49% of total pregnancies resulted in miscarriages/spontaneous abortions for the case group as compared with 4.98% in the control group. The percentage of childhood death in the case group was 13.5 as compared to 4.68 in the control group. All these differences were statistically significant, some highly so. Because a high incidence rate of chromosomal aberrations was found in the abortuses and because most such aberrations are incompatible with survival, it is possible that mothers of Down's Syndrome babies constitute a group of women predisposed genetically to meiotic nondisjunction and the consequent high loss rate. Probably many of the cases of stillbirth and childhood deaths included in the total were accounted for by chromosomal aberrations also.
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pubmed:meshHeading |
pubmed-meshheading:157014-Abortion, Spontaneous,
pubmed-meshheading:157014-Adult,
pubmed-meshheading:157014-Chromosome Aberrations,
pubmed-meshheading:157014-Down Syndrome,
pubmed-meshheading:157014-Female,
pubmed-meshheading:157014-Fetal Death,
pubmed-meshheading:157014-Humans,
pubmed-meshheading:157014-Infant,
pubmed-meshheading:157014-Infant, Newborn,
pubmed-meshheading:157014-Infant Mortality,
pubmed-meshheading:157014-Maternal Age,
pubmed-meshheading:157014-Nigeria,
pubmed-meshheading:157014-Pregnancy
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pubmed:year |
1979
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pubmed:articleTitle |
Down's syndrome in Nigeria: pregnancy wastage in mothers of Down's syndrome.
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pubmed:publicationType |
Journal Article
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