Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-2-9
pubmed:abstractText
High blood pressure raises the risks of vascular dementia and cognitive dysfunction in older adults, by acting on the cerebral vasculature and directly on the brain itself. Clinical trials and observational studies have shown that treating hypertension to target (<140/90 mm Hg) not only lessens morbidity and mortality, but also improves quality of life and preserves cognitive function. Yet, only 34% of hypertensive Americans currently have their hypertension under control, despite widespread treatment. Although single drug therapy is effective in treating hypertension, most patients will require combination drug treatment. Combination therapy--typically a diuretic with an ACE inhibitor, an ARB, or a beta blocker--is appropriate for treatment of older patients, is well tolerated, and can effectively preserve cognitive function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0016-867X
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
20-2, 24
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Hypertension and cognitive function. Blood pressure regulation and cognitive function: a review of the literature.
pubmed:affiliation
Georgetown University, Washington, DC, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't