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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-5-27
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pubmed:abstractText |
This is the final section of an intermediate phase of generalizations dealing with aspects of enhancers. It is concluded that a binding type protein(s) complex near a LTR segment. This creates destabilization of heterochromatin that allows transcription mechanisms. If this process is promoted by anomalous enhancer activity such as those produced by chemical inducers which modify chromatin states or cause hypomethylated enhancer regions, then normally repressed embryonic gene products, such as protooncogene growth factors, can be transcribed inappropriately to a specific developmental stage, eg post-embryonically.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0306-9877
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
12-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1569901-Animals,
pubmed-meshheading:1569901-Carcinogens,
pubmed-meshheading:1569901-Cell Differentiation,
pubmed-meshheading:1569901-DNA,
pubmed-meshheading:1569901-Enhancer Elements, Genetic,
pubmed-meshheading:1569901-Fetal Proteins,
pubmed-meshheading:1569901-Humans,
pubmed-meshheading:1569901-Methylation,
pubmed-meshheading:1569901-Models, Biological,
pubmed-meshheading:1569901-Proto-Oncogenes
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pubmed:year |
1992
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pubmed:articleTitle |
Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: XXVIII. Intermediate generalizations (Part C).
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pubmed:affiliation |
Canadian Institute of Theoretical Biology, Scott's Bay, Nova Scotia.
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pubmed:publicationType |
Journal Article
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