Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-2-17
pubmed:abstractText
The purpose of this study was to evaluate the capacity of high-resolution magnetic resonance imaging (MRI) to visualize the normal anatomic features of the human hippocampus in vitro, using high field imaging equipment, parameters, and acquisition times appropriate for imaging human subjects in vivo. This research compared high field, high-resolution MRI of formalin-fixed normal human hippocampus specimens to histologic sectioning of the same hippocampus samples. Four specimens were evaluated using an 8 Tesla (T), 80 cm bore whole-body MRI scanner equipped with a 12.7 cm single strut transverse electromagnetic resonator (TEM) coil. Hahn spin echo images were acquired with a repetition time (TR) of 800 msec, echo times (TE) of 20, 50, 90, and 134 msec, and an acquisition time (TA) of 3.25 min. The image quality was superb with demonstration of most of the features of the hippocampus. High field, high-resolution MRI can be used to depict multiple layers of the formalin-fixed human hippocampus in vitro using an 8 T whole-body scanner, a TEM coil, and short acquisition times compatible with human imaging in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0897-3806
pubmed:author
pubmed:copyrightInfo
Copyright 2005 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
88-91
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
High-resolution 8 Tesla imaging of the formalin-fixed normal human hippocampus.
pubmed:affiliation
Department of Radiology, University Hospital, Ohio State University, Columbus, Ohio 43210-1228, USA. chakeres-1@medctr.osu.edu
pubmed:publicationType
Journal Article