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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
2
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pubmed:dateCreated |
2005-2-7
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pubmed:abstractText |
2-(18)F-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine (2-(18)F-fluoro-A-85380) is a PET radioligand that is specific for nicotinic acetylcholine receptors (nAChRs) and has a high affinity for the alpha(4)beta(2) subtype. The purpose of this study was to evaluate different strategies to quantify 2-(18)F-fluoro-A-85380 binding in healthy nonsmoking human volunteers.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0161-5505
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
240-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15695782-Adult,
pubmed-meshheading:15695782-Azetidines,
pubmed-meshheading:15695782-Brain,
pubmed-meshheading:15695782-Brain Mapping,
pubmed-meshheading:15695782-Humans,
pubmed-meshheading:15695782-Image Interpretation, Computer-Assisted,
pubmed-meshheading:15695782-Male,
pubmed-meshheading:15695782-Metabolic Clearance Rate,
pubmed-meshheading:15695782-Positron-Emission Tomography,
pubmed-meshheading:15695782-Pyridines,
pubmed-meshheading:15695782-Radioisotope Dilution Technique,
pubmed-meshheading:15695782-Radiopharmaceuticals,
pubmed-meshheading:15695782-Receptors, Nicotinic,
pubmed-meshheading:15695782-Tissue Distribution
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pubmed:year |
2005
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|
pubmed:articleTitle |
In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18F-fluoro-A-85380 and PET.
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pubmed:affiliation |
Service Hospitalier Frédéric Joliot, Departement de Recherche Medicale/Direction des Sciences du Vivant, Commissariat à l'Energie Atomique, F-91406 Orsay, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
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