Linked Life Data

15694123

Source:http://linkedlifedata.com/resource/pubmed/id/15694123

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-2-7
pubmed:abstractText
Filamentous fungi have long been used for the production of metabolites and enzymes. With developments in genetic engineering and molecular biology, filamentous fungi have also achieved increased attention as hosts for recombinant DNA. However, the production levels of non-fungal proteins are usually low. Despite the achievements obtained using molecular tools, the heterologous protein loss caused by extracellular fungal protease degradation persists. This review provides an overview of the potential bioprocessing strategies that can be applied to inhibit protease activity thereby enhancing heterologous protein production.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0734-9750
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
115-29
pubmed:dateRevised
2006-7-7
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Bioprocessing strategies to improve heterologous protein production in filamentous fungal fermentations.
pubmed:affiliation
Department of Chemical Engineering, Ohio University, Athens, OH 45701, USA.
pubmed:publicationType
Journal Article