rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2005-2-4
|
pubmed:abstractText |
Graft-versus-leukemia (GVL) effect is an essential component in the course of allogeneic stem cell transplantation (SCT). However, both prevention and treatment of established graft-versus-host disease (GVHD), including with drugs such as cyclosporine, can suppress GVL effects. Mycophenolate mofetil (MMF) is becoming a standard of care in SCT recipients for better prevention of GVHD as well as for promoting stem cell engraftment.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0340-7004
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
54
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
383-8
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15692848-Animals,
pubmed-meshheading:15692848-Cyclin D1,
pubmed-meshheading:15692848-Cytotoxicity, Immunologic,
pubmed-meshheading:15692848-Enzyme Inhibitors,
pubmed-meshheading:15692848-Female,
pubmed-meshheading:15692848-Graft vs Leukemia Effect,
pubmed-meshheading:15692848-Immunotherapy, Adoptive,
pubmed-meshheading:15692848-Injections, Intraperitoneal,
pubmed-meshheading:15692848-Interleukin-2,
pubmed-meshheading:15692848-Killer Cells, Lymphokine-Activated,
pubmed-meshheading:15692848-Leukemia, B-Cell,
pubmed-meshheading:15692848-Male,
pubmed-meshheading:15692848-Mice,
pubmed-meshheading:15692848-Mice, Inbred BALB C,
pubmed-meshheading:15692848-Mice, Inbred C57BL,
pubmed-meshheading:15692848-Mycophenolic Acid,
pubmed-meshheading:15692848-Stem Cell Transplantation,
pubmed-meshheading:15692848-Survival Rate,
pubmed-meshheading:15692848-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:15692848-Transplantation, Homologous,
pubmed-meshheading:15692848-Whole-Body Irradiation
|
pubmed:year |
2005
|
pubmed:articleTitle |
Mycophenolate mofetil does not suppress the graft-versus-leukemia effect or the activity of lymphokine-activated killer (LAK) cells in a murine model.
|
pubmed:affiliation |
Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah-Hebrew University Medical Center, PO Box 12000, 91120, Jerusalem, Israel. shapiram@hadassah.org.il
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|