Source:http://linkedlifedata.com/resource/pubmed/id/15690378
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2005-2-3
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pubmed:abstractText |
The mechanisms by which maternal diabetes causes malformations in the offspring have yet to be elucidated. The purpose of this report is twofold: first, to describe three male infants born with multiple congenital anomalies and megalourethra, a defect which has not been previously reported in infants of women with diabetes; and second, to indicate that the defects seen in association with megalourethra in these three infants are similar to those seen as a consequence of abnormalities in sonic hedgehog, suggesting that maternal diabetes may affect sonic hedgehog expression in susceptible tissues during critical stages of development.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1552-4825
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2004 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
132A
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-7
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pubmed:dateRevised |
2008-5-21
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pubmed:meshHeading |
pubmed-meshheading:15690378-Adult,
pubmed-meshheading:15690378-Diabetes, Gestational,
pubmed-meshheading:15690378-Fatal Outcome,
pubmed-meshheading:15690378-Female,
pubmed-meshheading:15690378-Humans,
pubmed-meshheading:15690378-Infant, Newborn,
pubmed-meshheading:15690378-Male,
pubmed-meshheading:15690378-Pancreas,
pubmed-meshheading:15690378-Penis,
pubmed-meshheading:15690378-Pregnancy,
pubmed-meshheading:15690378-Urethra
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pubmed:year |
2005
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pubmed:articleTitle |
Megalourethra: A report of three cases associated with maternal diabetes and a review of the literature--is sonic hedgehog the common pathway?
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pubmed:affiliation |
Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
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