Linked Life Data

15686939

Source:http://linkedlifedata.com/resource/pubmed/id/15686939

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-2-2
pubmed:abstractText
The pseudopeptide pyrrolidinedione natural products moiramide B and andrimid represent a new class of antibiotics that target bacterial fatty acid biosynthesis. Structure-activity relationship (SAR) studies revealed a high degree of variability for the fatty acid side chain, allowing optimization of physicochemical parameters, and a restricted SAR for the pyrrolidinedione group, indicating major relevance of this subunit for efficient target binding.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1189-92
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Pyrrolidinedione derivatives as antibacterial agents with a novel mode of action.
pubmed:affiliation
Department of Medicinal Chemistry, Bayer HealthCare AG, D-42096 Wuppertal, Germany.
pubmed:publicationType
Journal Article