Linked Life Data

15686101

Source:http://linkedlifedata.com/resource/pubmed/id/15686101

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-2-2
pubmed:abstractText
We investigated how patients with cerebellar degeneration control fingertip forces to resist a perturbation imposed on a handheld load. Patients and healthy sex- and age-matched control subjects held an instrumented receptacle between the index finger and thumb. A weight was dropped into the receptacle either unexpectedly from the experimenter's hand with the subject being blindfolded or expectedly from the subject's opposite hand. This paradigm allowed us to study predictive and reactive modes of finger force control. Patients generated an overshoot of grip force, irrespective of whether the weight was dropped expectedly or unexpectedly. When the weight was dropped from the experimenter's hand, grip force lagged behind the load perturbation at impact in patients and controls. When the weight was dropped expectedly from the subject's opposite hand, healthy subjects started to increase grip force prior to the release of the weight. This observation is indicative for a predictive mode of force control. In contrast, the grip force profile of cerebellar patients was not processed in anticipation of the time of impact when the weight was dropped from the opposite hand. Our data suggest involvement of cerebellar circuits in a predictive, but less in a reactive, mode of fingertip force control during manipulative behavior.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1473-4222
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-35
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Predictive and reactive finger force control during catching in cerebellar degeneration.
pubmed:affiliation
Department of Neurology and Clinical Neurophysiology, Academic Hospital Bogenhausen, Technical University of Munich, Munich, Germany. Dr.Dennis.Nowak@gmx.de
pubmed:publicationType
Journal Article, Comparative Study