|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2005-2-1
|
|
pubmed:abstractText |
Inhibitory G-protein-coupled receptors have demonstrated potential in treatment of gastroesophageal reflux disease (GERD) through actions on vagal afferent signaling. Metabotropic glutamate receptors (mGluR) belong to this receptor family and have great pharmacologic and molecular diversity, with 8 subtypes. We investigated mGluR in the vagal system of humans and other species.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0016-5085
|
|
pubmed:author |
pubmed-author:BlackshawL AshleyLA,
pubmed-author:ColdwellJonathan RJR,
pubmed-author:CooperNicole JNJ,
pubmed-author:HulanderMalinM,
pubmed-author:LehmannAndersA,
pubmed-author:MartinChris MCM,
pubmed-author:MattssonJan PJP,
pubmed-author:O'DonnellTracey ATA,
pubmed-author:PageAmanda JAJ,
pubmed-author:UmaerusMiaM,
pubmed-author:YoungRichard LRL
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
128
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
402-10
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15685551-Afferent Pathways,
pubmed-meshheading:15685551-Animals,
pubmed-meshheading:15685551-Base Sequence,
pubmed-meshheading:15685551-DNA Primers,
pubmed-meshheading:15685551-Dogs,
pubmed-meshheading:15685551-Humans,
pubmed-meshheading:15685551-Mechanoreceptors,
pubmed-meshheading:15685551-Neurons, Afferent,
pubmed-meshheading:15685551-Nodose Ganglion,
pubmed-meshheading:15685551-Polymerase Chain Reaction,
pubmed-meshheading:15685551-Rats,
pubmed-meshheading:15685551-Receptors, Metabotropic Glutamate,
pubmed-meshheading:15685551-Vagus Nerve
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons.
|
|
pubmed:affiliation |
Nerve-Gut Research Laboratory, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
