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pubmed-article:15682517pubmed:abstractTextSerum samples from people exposed to sheep at a research facility were evaluated by a commercial laboratory and resulted in an overall Coxiella burnetii seroprevalence of 75%. We interviewed individuals to determine exposure history and compatible illness, and retested their sera. Analysis indicated that the commercial laboratory was misinterpreting its results; when corrected, the seroprevalence dropped to 27%. Test kits of the brand used by the commercial laboratory gave equivalent results to the in-house CDC assay when tested in parallel at CDC. Upon final analysis, only the attending veterinarian was confirmed as a Q fever case. This event resulted in increased risk reduction protocols at the research facility and improved public health communication among health authorities. This pseudoepidemic resulted from a lapse in laboratory quality control for testing. Similar errors can be avoided through standardization and improved review of laboratory procedures.lld:pubmed
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pubmed-article:15682517pubmed:articleTitlePseudoepidemic of Q fever at an animal research facility.lld:pubmed
pubmed-article:15682517pubmed:affiliationFlorida Department of Health, Tallahassee, Florida, USA. lisa_conti@doh.state.fl.uslld:pubmed
pubmed-article:15682517pubmed:publicationTypeJournal Articlelld:pubmed