Linked Life Data

15678482

Source:http://linkedlifedata.com/resource/pubmed/id/15678482

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-3-7
pubmed:abstractText
We demonstrate that breath holding of short durations may confound functional magnetic resonance imaging (fMRI) studies. Some subjects may hold their breath for a short time during task performance, especially if the task is challenging. Breath holding may therefore need to be considered specifically when interpreting fMRI experiments. We studied the temporal and spatial characteristics of cerebral T2*-weighted signal during short periods of breath holding by seven individuals in a 3-tesla MR scanner. We demonstrate that breath-holds as short as 3 s can result in regions of significant cerebral activation. More interestingly, we show that focal activation remains present when the data is analysed in a number of different ways, including analyses that correct for motion and model the task epoch as if it were 10 times longer than the actual breath-hold length. These findings have potential relevance for many researchers carrying out fMRI studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1065-9471
pubmed:author
pubmed:copyrightInfo
(c) 2005 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
284-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Brief breath holding may confound functional magnetic resonance imaging studies.
pubmed:affiliation
Brain Research Institute, Melbourne, Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't