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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-28
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pubmed:abstractText |
Coronary artery bypass graft surgery is associated with a considerable 2-year mortality rate. Gene polymorphisms of the renin-angiotensin system may be associated with the risk of hypertension and cardiovascular disease. The angiotensin I-converting enzyme DD genotype has recently been identified as independent predictor of the outcome after coronary artery bypass graft surgery. Genetic factors of the clotting system may be related to the risk of myocardial infarction and restenosis after coronary interventions. The aims of the present study were to investigate whether gene polymorphisms of the renin-angiotensin system (angiotensinogen 235 M/T, angiotensin II type 1 receptor 1166 A/C) or the clotting system (glycoprotein IIIa PlA1/PlA2 and factor V Leiden 1691 G/A) are associated with the outcome after coronary artery bypass grafting.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alanine,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensinogen,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine,
http://linkedlifedata.com/resource/pubmed/chemical/Factor V,
http://linkedlifedata.com/resource/pubmed/chemical/Integrin beta3,
http://linkedlifedata.com/resource/pubmed/chemical/Methionine,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/Threonine,
http://linkedlifedata.com/resource/pubmed/chemical/factor V Leiden
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0167-5273
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
98
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15676177-Adult,
pubmed-meshheading:15676177-Aged,
pubmed-meshheading:15676177-Aged, 80 and over,
pubmed-meshheading:15676177-Alanine,
pubmed-meshheading:15676177-Angiotensinogen,
pubmed-meshheading:15676177-Blood Coagulation,
pubmed-meshheading:15676177-Blood Pressure,
pubmed-meshheading:15676177-Coronary Artery Bypass,
pubmed-meshheading:15676177-Coronary Artery Disease,
pubmed-meshheading:15676177-Cysteine,
pubmed-meshheading:15676177-Factor V,
pubmed-meshheading:15676177-Female,
pubmed-meshheading:15676177-Follow-Up Studies,
pubmed-meshheading:15676177-Genotype,
pubmed-meshheading:15676177-Humans,
pubmed-meshheading:15676177-Integrin beta3,
pubmed-meshheading:15676177-Male,
pubmed-meshheading:15676177-Methionine,
pubmed-meshheading:15676177-Middle Aged,
pubmed-meshheading:15676177-Myocardial Contraction,
pubmed-meshheading:15676177-Polymorphism, Genetic,
pubmed-meshheading:15676177-Receptor, Angiotensin, Type 1,
pubmed-meshheading:15676177-Renin-Angiotensin System,
pubmed-meshheading:15676177-Stroke Volume,
pubmed-meshheading:15676177-Threonine,
pubmed-meshheading:15676177-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Renin-angiotensin system and haemostasis gene polymorphisms and outcome after coronary artery bypass graft surgery.
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pubmed:affiliation |
Department of Epidemiology and Social Medicine, Ernst Moritz Arndt University, Walther Rathenau Str. 48, D-17487 Greifswald, Germany. voelzke@uni-greifswald.de
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pubmed:publicationType |
Journal Article,
Comparative Study
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