rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1992-5-15
|
pubmed:databankReference |
|
pubmed:abstractText |
An upstream region of the human estrogen receptor gene (ER) spanning from -2776 to -38 in relation to a previously described exon 1 was sequenced and analyzed for the possible presence of open reading frames (ORF) and regulatory motifs. We identified a long 459 bp ORF beginning at -2301. Most of the transcriptional regulatory motifs present within the ER upstream sequence are distributed either upstream or downstream of this long ORF which displays a TATA box, a CACC motif and a canonical cap site in the 5' flanking region.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0006-291X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
31
|
pubmed:volume |
183
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
996-1002
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1567414-Base Sequence,
pubmed-meshheading:1567414-Chromosome Mapping,
pubmed-meshheading:1567414-Humans,
pubmed-meshheading:1567414-Molecular Sequence Data,
pubmed-meshheading:1567414-Reading Frames,
pubmed-meshheading:1567414-Receptors, Estrogen,
pubmed-meshheading:1567414-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:1567414-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1567414-Transcription, Genetic
|
pubmed:year |
1992
|
pubmed:articleTitle |
Analysis of upstream sequences of the human estrogen receptor gene.
|
pubmed:affiliation |
Istituto di Chimica Biologica, Università degli Studi di Ferrara, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|