|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2005-1-26
|
|
pubmed:abstractText |
Toll-like receptors (TLRs), which recognize microbial products, have an important role in the host innate immune response. The purpose of the present study was to determine whether activation of these receptors leads to development of keratitis and to assess the role of the common adaptor molecule myeloid differentiation factor-88 (MyD88).
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,3-bis(palmitoyloxy)-2-propyl-1-pal...,
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CXC,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Myd88 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Myeloid Differentiation Factor 88,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr9 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 9
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0146-0404
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
46
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
589-95
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:15671286-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:15671286-Animals,
pubmed-meshheading:15671286-Antigens, Differentiation,
pubmed-meshheading:15671286-Chemokines, CXC,
pubmed-meshheading:15671286-Corneal Stroma,
pubmed-meshheading:15671286-CpG Islands,
pubmed-meshheading:15671286-Cysteine,
pubmed-meshheading:15671286-DNA-Binding Proteins,
pubmed-meshheading:15671286-Epithelium, Corneal,
pubmed-meshheading:15671286-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:15671286-Keratitis,
pubmed-meshheading:15671286-Lipopolysaccharides,
pubmed-meshheading:15671286-Lipoproteins,
pubmed-meshheading:15671286-Mice,
pubmed-meshheading:15671286-Mice, Inbred C57BL,
pubmed-meshheading:15671286-Mice, Knockout,
pubmed-meshheading:15671286-Myeloid Differentiation Factor 88,
pubmed-meshheading:15671286-Neutrophil Infiltration,
pubmed-meshheading:15671286-Neutrophils,
pubmed-meshheading:15671286-Receptors, Cell Surface,
pubmed-meshheading:15671286-Receptors, Immunologic,
pubmed-meshheading:15671286-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15671286-Toll-Like Receptor 2,
pubmed-meshheading:15671286-Toll-Like Receptor 4,
pubmed-meshheading:15671286-Toll-Like Receptor 9
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.
|
|
pubmed:affiliation |
Department of Ophthalmology, Case Western University, Cleveland, OH 44106-7286, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
