Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-1-25
pubmed:abstractText
A 50% rate of early virological failure associated with the selection of resistance mutations was seen in a group of 14 antiretroviral-naive adults who initiated highly active antiretroviral therapy with tenofovir and didanosine plus efavirenz or nevirapine. At month 6, the mutations detected were K65R, L74V, L100I, K103N/R/T, Y181C and G190E/Q/S. These results argue against the use of tenofovir plus didanosine in HIV-infected antiretroviral-naive adults even when the third drug is a non-nucleoside reverse transcriptase inhibitor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0269-9370
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-5
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:15668550-Adenine, pubmed-meshheading:15668550-Adult, pubmed-meshheading:15668550-Aged, pubmed-meshheading:15668550-Antiretroviral Therapy, Highly Active, pubmed-meshheading:15668550-Benzoxazines, pubmed-meshheading:15668550-Didanosine, pubmed-meshheading:15668550-Drug Resistance, Viral, pubmed-meshheading:15668550-Drug Therapy, Combination, pubmed-meshheading:15668550-Female, pubmed-meshheading:15668550-HIV Infections, pubmed-meshheading:15668550-HIV-1, pubmed-meshheading:15668550-Humans, pubmed-meshheading:15668550-Male, pubmed-meshheading:15668550-Middle Aged, pubmed-meshheading:15668550-Nevirapine, pubmed-meshheading:15668550-Oxazines, pubmed-meshheading:15668550-Phosphonic Acids, pubmed-meshheading:15668550-RNA, Viral, pubmed-meshheading:15668550-Reverse Transcriptase Inhibitors
pubmed:year
2005
pubmed:articleTitle
Early virological failure in treatment-naive HIV-infected adults receiving didanosine and tenofovir plus efavirenz or nevirapine.
pubmed:affiliation
Infectious Diseases Unit, Hospital Clinic, University of Barcelona, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't