rdf:type |
|
lifeskim:mentions |
umls-concept:C0013227,
umls-concept:C0013682,
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0026377,
umls-concept:C0185117,
umls-concept:C0332161,
umls-concept:C1373200,
umls-concept:C1533691,
umls-concept:C1546465,
umls-concept:C1705175,
umls-concept:C1705176,
umls-concept:C1705177,
umls-concept:C1705178,
umls-concept:C1709059,
umls-concept:C1882348,
umls-concept:C2911684
|
pubmed:issue |
1
|
pubmed:dateCreated |
2005-1-25
|
pubmed:abstractText |
To construct different conformations of a plasmid DNA/vector complex (pcDNA3.1/IFN-gamma-ASOR-PLL) and transfect cells of the hepatoma cell line BEL7402 to investigate the optimal conformation of the complex for improved expression efficiency in the target cell.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1443-9611
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
6
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
37-42
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:15667557-Antineoplastic Agents,
pubmed-meshheading:15667557-Asialoglycoproteins,
pubmed-meshheading:15667557-Carcinoma, Hepatocellular,
pubmed-meshheading:15667557-DNA,
pubmed-meshheading:15667557-Drug Carriers,
pubmed-meshheading:15667557-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15667557-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15667557-Genetic Vectors,
pubmed-meshheading:15667557-Humans,
pubmed-meshheading:15667557-Interferon-gamma,
pubmed-meshheading:15667557-Liver Neoplasms,
pubmed-meshheading:15667557-Orosomucoid,
pubmed-meshheading:15667557-Plasmids,
pubmed-meshheading:15667557-Polylysine,
pubmed-meshheading:15667557-Protein Conformation,
pubmed-meshheading:15667557-Tumor Cells, Cultured
|
pubmed:year |
2005
|
pubmed:articleTitle |
Modulation of the molecular conformation of a hepatocyte-targeting gene drug in order to improve its expression efficiency in vitro.
|
pubmed:affiliation |
Department of Gastroenterology, the Second XiangYa Hospital, Central South University and Sheng Life Gene Drug Development Company, Changsha, Hunan Province, China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|