Source:http://linkedlifedata.com/resource/pubmed/id/15661634
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2005-1-21
|
pubmed:abstractText |
Pharmacological agents have shown limited efficacy and consistency in the treatment of drug addiction. Hence, the development of new medications with improved long-term efficacy and reduced side effects should be given a high priority given the costs to society associated with drug abuse and drug-related pathologies. Neurochemical systems can be significantly altered by repeated exposure to drugs of abuse. These long-term molecular and neurochemical changes might, in turn, explain the core features of addiction--the compulsive seeking and taking of the drug--as well as the risk of relapse.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1471-4892
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
107-18
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15661634-Alcoholism,
pubmed-meshheading:15661634-Clinical Trials as Topic,
pubmed-meshheading:15661634-Cocaine-Related Disorders,
pubmed-meshheading:15661634-Humans,
pubmed-meshheading:15661634-Naltrexone,
pubmed-meshheading:15661634-Narcotic Antagonists,
pubmed-meshheading:15661634-Nicotine,
pubmed-meshheading:15661634-Opioid-Related Disorders,
pubmed-meshheading:15661634-Structure-Activity Relationship,
pubmed-meshheading:15661634-Substance-Related Disorders,
pubmed-meshheading:15661634-Tobacco Use Disorder
|
pubmed:year |
2005
|
pubmed:articleTitle |
Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving.
|
pubmed:affiliation |
Department of Biology, Centre of Excellence for Drug Discovery in Psychiatry, GlaxoSmithKline Pharmaceuticals, 37135 Verona, Italy. Christian_A_Heidbreder@gsk.com
|
pubmed:publicationType |
Journal Article,
Review
|