rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9
|
pubmed:dateCreated |
2005-4-27
|
pubmed:abstractText |
A high density of single nucleotide polymorphism (SNP) coverage on the genome is desirable and often an essential requirement for population genetics studies. Region-specific or chromosome-specific linkage studies also benefit from the availability of as many high quality SNPs as possible. The availability of millions of SNPs from both Perlegen and the public domain and the development of an efficient microarray-based assay for genotyping SNPs has brought up some interesting analytical challenges. Effective methods for the selection of optimal subsets of SNPs spanning the genome and methods for accurately calling genotypes from probe hybridization patterns have enabled the development of a new microarray-based system for robustly genotyping over 100,000 SNPs per sample.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1367-4803
|
pubmed:author |
pubmed-author:BartellDanD,
pubmed-author:CawleySimonS,
pubmed-author:ChilesRichardR,
pubmed-author:DiXiaojunX,
pubmed-author:DongShoulianS,
pubmed-author:HuangJingJ,
pubmed-author:HubbellEarlE,
pubmed-author:JonesKeith WKW,
pubmed-author:KennedyGiulia CGC,
pubmed-author:KulpDavidD,
pubmed-author:LiuGuoyingG,
pubmed-author:MatsuzakiHajimeH,
pubmed-author:MeiRuiR,
pubmed-author:ShenMei-meiMM,
pubmed-author:WebsterTeresa ATA,
pubmed-author:YangGeoffreyG
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1958-63
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:15657097-Algorithms,
pubmed-meshheading:15657097-Computer Simulation,
pubmed-meshheading:15657097-DNA Mutational Analysis,
pubmed-meshheading:15657097-Genetic Testing,
pubmed-meshheading:15657097-Genotype,
pubmed-meshheading:15657097-Humans,
pubmed-meshheading:15657097-Models, Genetic,
pubmed-meshheading:15657097-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:15657097-Polymorphism, Single Nucleotide,
pubmed-meshheading:15657097-Sequence Alignment,
pubmed-meshheading:15657097-Sequence Analysis, DNA,
pubmed-meshheading:15657097-Software
|
pubmed:year |
2005
|
pubmed:articleTitle |
Dynamic model based algorithms for screening and genotyping over 100 K SNPs on oligonucleotide microarrays.
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pubmed:affiliation |
Affymetrix, Inc., Santa Clara, CA 95051, USA. xiaojun_di@affymetrix.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies,
Validation Studies
|