| pubmed-article:15657059 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C0010656 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C0041904 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C0162493 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C0013138 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:15657059 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:15657059 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:15657059 | pubmed:dateCreated | 2005-3-21 | lld:pubmed |
| pubmed-article:15657059 | pubmed:abstractText | The Drosophila steroid hormone ecdysone mediates cell death during metamorphosis by regulating the transcription of a number of cell death genes. The apical caspase DRONC is known to be transcriptionally regulated by ecdysone during development. Here we demonstrate that ecdysone also regulates the transcription of DRICE, a major effector caspase and a downstream target for DRONC in the fly. Using RNA interference in an ecdysone-responsive Drosophila cell line, we show that drice up-regulation is essential for apoptosis induced by ecdysone. We also show that drice expression is specifically controlled by the ecdysone-regulated transcription factor BR-C. Combined with previous observations, our results indicate that transcriptional regulation of the components of the core apoptotic machinery plays a key role in hormone-regulated programmed cell death during Drosophila development. | lld:pubmed |
| pubmed-article:15657059 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15657059 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15657059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15657059 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15657059 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:15657059 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:15657059 | pubmed:author | pubmed-author:KumarSharadS | lld:pubmed |
| pubmed-article:15657059 | pubmed:author | pubmed-author:CakourosDimit... | lld:pubmed |
| pubmed-article:15657059 | pubmed:author | pubmed-author:KilpatrickZoé... | lld:pubmed |
| pubmed-article:15657059 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15657059 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:15657059 | pubmed:volume | 280 | lld:pubmed |
| pubmed-article:15657059 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15657059 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15657059 | pubmed:pagination | 11981-6 | lld:pubmed |
| pubmed-article:15657059 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
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| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
| pubmed-article:15657059 | pubmed:meshHeading | pubmed-meshheading:15657059... | lld:pubmed |
| pubmed-article:15657059 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15657059 | pubmed:articleTitle | Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells. | lld:pubmed |
| pubmed-article:15657059 | pubmed:affiliation | Hanson Institute, Institute of Medical and Veterinary Science, PO Box 14, Rundle Mall, Adelaide, SA 5000, Australia. | lld:pubmed |
| pubmed-article:15657059 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15657059 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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