Linked Life Data

15652284

Source:http://linkedlifedata.com/resource/pubmed/id/15652284

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-1-17
pubmed:abstractText
The in vitro biological activity of nine frequently used medicinal plants in South Africa was assessed and re-assessed after various lengths of storage. The plants investigated were Alepidea amatymbica, Leonotis leonurus, Drimia robusta, Vernonia colorata, Merwilla natalensis, Eucomis autumnalis, Bowiea volubilis, Helichrysum cymosum and Siphonochilus aethiopicus. Water, ethanol and hexane extracts of fresh, 90-day-old and 1-year-old material were assayed for antibacterial activity against four strains of bacteria and for COX-1 inhibition activity. TLC-fingerprints of the fresh and stored extracts were produce to document chemical changes. Alepidea amatymbica, Eucomis autumnalis, Helichrysum cymosum, Leonotis leonurus, Siphonochilus aethiopicus and Vernonia colorata were investigated further as to the effect of 1 year's storage. Elevated temperature and humidity (55 degrees C and 100% relative humidity) were used to accelerate the ageing process of Alepidea amatymbica, Leonotis leonurus and Vernonia colorata plant material for further investigation. The TLC-fingerprints indicated that there was chemical breakdown during storage in certain species. The degree of changes in biological activity and chemistry due to storage were species-specific. In general, antibacterial activity was retained in most species while COX-1 inhibition activity was lost rapidly.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0378-8741
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
97
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-15
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Effect of storage on the chemical composition and biological activity of several popular South African medicinal plants.
pubmed:affiliation
Faculty of Science and Agriculture, University of KwaZulu Natal, Pietermaritzburg, Private Bag X01, Scottsville, South Africa.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't