Source:http://linkedlifedata.com/resource/pubmed/id/15650828
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2005-4-12
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pubmed:abstractText |
The insulin-like growth factor system, which includes insulin-like growth factors (IGF-I and IGF-II), IGF receptors (IGF-IR and IGF-IIR) and IGF binding proteins (IGFBPs), plays an important role in epithelial growth, anti-apoptosis and mitogenesis. There is a growing body of evidence showing that IGFs control growth and proliferation of several types of cancer. This review introduces the latest information on the biology of the IGF system and its pathophysiological role in the development of colorectal cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0179-1958
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-20
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pubmed:meshHeading |
pubmed-meshheading:15650828-Animals,
pubmed-meshheading:15650828-Apoptosis,
pubmed-meshheading:15650828-Cell Division,
pubmed-meshheading:15650828-Colorectal Neoplasms,
pubmed-meshheading:15650828-Humans,
pubmed-meshheading:15650828-Somatomedins,
pubmed-meshheading:15650828-Tumor Markers, Biological
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pubmed:year |
2005
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pubmed:articleTitle |
The role of the insulin-like growth factor system in colorectal cancer: review of current knowledge.
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pubmed:affiliation |
University Department of Surgery, Royal Free and University College Medical School, University College London, Rowland Hill Street, London, NW3 2PF, UK.
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pubmed:publicationType |
Journal Article,
Review
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