Source:http://linkedlifedata.com/resource/pubmed/id/15650046
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2005-2-18
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pubmed:abstractText |
Recent data emphasized the implication of polymerase gamma (POLG) CAG repeats in infertility, making it a very attractive gene for study. A comparison of POLG CAG repeats in infertile and fertile men showed a clear association between the absence of the usual 10-CAG allele and male infertility, excluding azoospermia. It has also been suggested that the POLG gene polymorphism should be considered as a possible contributing factor in unexplained couple infertility where semen parameters are normal. In this study, we investigated the POLG CAG repeats, in a well-defined population of patients with severe male factor infertility.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0268-1161
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
736-40
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pubmed:meshHeading |
pubmed-meshheading:15650046-Adult,
pubmed-meshheading:15650046-Case-Control Studies,
pubmed-meshheading:15650046-DNA, Mitochondrial,
pubmed-meshheading:15650046-DNA-Directed DNA Polymerase,
pubmed-meshheading:15650046-Female,
pubmed-meshheading:15650046-Gene Frequency,
pubmed-meshheading:15650046-Homozygote,
pubmed-meshheading:15650046-Humans,
pubmed-meshheading:15650046-Infertility, Male,
pubmed-meshheading:15650046-Male,
pubmed-meshheading:15650046-Mutation,
pubmed-meshheading:15650046-Pregnancy,
pubmed-meshheading:15650046-Pregnancy Rate,
pubmed-meshheading:15650046-Reproductive Techniques, Assisted,
pubmed-meshheading:15650046-Severity of Illness Index,
pubmed-meshheading:15650046-Trinucleotide Repeats
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pubmed:year |
2005
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pubmed:articleTitle |
Is the CAG repeat of mitochondrial DNA polymerase gamma (POLG) associated with male infertility? A multi-centre French study.
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pubmed:affiliation |
Laboratoire de Biologie de la Reproduction, Service de Génétique Moléculaire, CHU-Hôpital Nord, Saint Etienne, France.
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pubmed:publicationType |
Journal Article,
Multicenter Study
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