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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-5-18
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pubmed:abstractText |
The effect of melatonin as well as pinealectomy on the basal and K(+)-evoked release of vasopressin and oxytocin from the neurointermediate lobes in vitro was determined. Pineal removal resulted in a diminution of vasopressin and oxytocin release from the neurointermediate lobes in vitro. Melatonin (10(-3) or 10(-6) M/l) increased vasopressin and oxytocin release from neurointermediate lobes of sham-operated rats. Nevertheless, when pinealectomized rats served as donors of the neurointermediate lobes, melatonin (10(-3) or 10(-6) M/l) increased vasopressin release under basal conditions. For the same tissue, melatonin did not affect the oxytocin release either under basal conditions or during depolarization due to excess potassium. When 10(-7) M/l melatonin was used, no changes in either vasopressin or oxytocin release were observed in vitro.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0742-3098
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1564628-Animals,
pubmed-meshheading:1564628-Male,
pubmed-meshheading:1564628-Melatonin,
pubmed-meshheading:1564628-Oxytocin,
pubmed-meshheading:1564628-Pineal Gland,
pubmed-meshheading:1564628-Pituitary Gland, Posterior,
pubmed-meshheading:1564628-Rats,
pubmed-meshheading:1564628-Vasopressins
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pubmed:year |
1992
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pubmed:articleTitle |
Melatonin, pinealectomy, and release of neurohypophysial hormones: in vitro studies.
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pubmed:affiliation |
Department of Pathophysiology, School of Medicine, Lodz, Poland.
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pubmed:publicationType |
Journal Article
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