|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2005-1-11
|
|
pubmed:abstractText |
Interleukin 6 (IL-6) is a key proinflammatory cytokine in the systemic inflammatory response syndrome (SIRS). A G-->C polymorphism at position -174 of the IL-6 gene is associated with an adverse outcome in a number of inflammatory diseases, although its association with sepsis as an outcome remains unclear. We tested the hypothesis that specific haplotype clades of IL-6 may be associated with an outcome of SIRS.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0003-9926
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
10
|
|
pubmed:volume |
165
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
75-82
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15642878-Adult,
pubmed-meshheading:15642878-Aged,
pubmed-meshheading:15642878-Cohort Studies,
pubmed-meshheading:15642878-Critical Illness,
pubmed-meshheading:15642878-Cysteine,
pubmed-meshheading:15642878-European Continental Ancestry Group,
pubmed-meshheading:15642878-Female,
pubmed-meshheading:15642878-Gene Frequency,
pubmed-meshheading:15642878-Genotype,
pubmed-meshheading:15642878-Glycine,
pubmed-meshheading:15642878-Great Britain,
pubmed-meshheading:15642878-Haplotypes,
pubmed-meshheading:15642878-Humans,
pubmed-meshheading:15642878-Interleukin-6,
pubmed-meshheading:15642878-Male,
pubmed-meshheading:15642878-Middle Aged,
pubmed-meshheading:15642878-Multiple Organ Failure,
pubmed-meshheading:15642878-Phenotype,
pubmed-meshheading:15642878-Polymorphism, Single Nucleotide,
pubmed-meshheading:15642878-Predictive Value of Tests,
pubmed-meshheading:15642878-Systemic Inflammatory Response Syndrome
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
The association of interleukin 6 haplotype clades with mortality in critically ill adults.
|
|
pubmed:affiliation |
University of British Columbia McDonald Research Laboratories/The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St Paul's Hospital, Vancouver, British Columbia V6Z 1Y6, Canada.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
