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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-13
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pubmed:abstractText |
To clarify the consequences of the valine/leucine polymorphism at position 247 of the beta(2)-glycoprotein I (beta(2)GPI) gene in patients with antiphospholipid syndrome (APS), by investigating the correlation between genotypes and the presence of anti-beta(2)GPI antibody. The reactivity of anti-beta(2)GPI antibodies was characterized using recombinant Val(247) and Leu(247) beta(2)GPI.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
212-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15641049-Adult,
pubmed-meshheading:15641049-Aged,
pubmed-meshheading:15641049-Antibodies, Anticardiolipin,
pubmed-meshheading:15641049-Antiphospholipid Syndrome,
pubmed-meshheading:15641049-Autoantibodies,
pubmed-meshheading:15641049-Female,
pubmed-meshheading:15641049-Glycoproteins,
pubmed-meshheading:15641049-Humans,
pubmed-meshheading:15641049-Leucine,
pubmed-meshheading:15641049-Male,
pubmed-meshheading:15641049-Middle Aged,
pubmed-meshheading:15641049-Molecular Conformation,
pubmed-meshheading:15641049-Polymorphism, Genetic,
pubmed-meshheading:15641049-Valine,
pubmed-meshheading:15641049-beta 2-Glycoprotein I
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pubmed:year |
2005
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pubmed:articleTitle |
Significance of valine/leucine247 polymorphism of beta2-glycoprotein I in antiphospholipid syndrome: increased reactivity of anti-beta2-glycoprotein I autoantibodies to the valine247 beta2-glycoprotein I variant.
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pubmed:affiliation |
Medicine II, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo 060-8638, Japan.
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pubmed:publicationType |
Journal Article
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