Linked Life Data

15640060

Source:http://linkedlifedata.com/resource/pubmed/id/15640060

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-1-10
pubmed:abstractText
Chromatin insulators, which define domains of transcriptional autonomy, are cis-acting elements of eukaryotes. They are located at the boundaries of differentially regulated genes and delimit their interactions by establishing independent chromatin structures. They can block chromosomal enhancers or silencers if they are located between promoters and enhancers or silencers, and protect against position effect. Recent studies focus on elucidating the molecular mechanism of insulator functions. Loop Model is the most predominant hypothesis while others are assumed. Study progress in this field sheds new light on the regulation of gene expression.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0253-9772
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
551-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
[The progress in the study of chromatin insulator].
pubmed:affiliation
Department of Molecular Biology, Third Military Medical University, Chongqing 400 038, China. mouse@mail.tmmu.com.cn
pubmed:publicationType
Journal Article, English Abstract, Review